Endocrine Abstracts

Although initially considered rare, the incidence of pancreatic neuroendocrine tumours (P-NETs) has progressively increased. A population-based study conducted in England and Wales (1986–1999) found that 5-year survival was 29% for non-functioning and 41% for functioning tumours when considering well-differentiated P-NETs. Traditional treatments show very limited effectiveness; novel targeted therapies are, therefore, required and identification of key molecules driving n...